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Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis. These are presently available as a topical cream, marketed by Novartis, under the brand Elidel®. A FDA has issued a public health consultive all about a conceivable chance of lymph node or even skin cancer from either apply of Elidel.

Pharmacology
Pimecrolimus is an ascomycin macrolactam derivative. It has been shown inside vitro that pimecrolimus binds to macrophilin-12 & inhibits calcineurin. So pimecrolimus inhibits T-cell activation by inhibiting the synthesis & release of cytokines from T-cells. Pimecrolimus likewise prevents a release of inflammatory cytokines & intermediator from either mast cells.

Pimecrolimus (Topical) - Healthtouch
Information for consumers in html format.

Elidel
Full prescribing information from RxList.

Elidel (pimecrolimus) Novartis - Canada
This site offers the approved Canadian patient and prescribing information for Elidel, as well as links to related press releases and eczema resources.

Food and Drug Administration (FDA) - Elidel Consumer Information
Patient FAQ in html format with a link to approved labeling (as pdf).b

Elidel Eczema Treatment
Official pharmaceutical website with information for patients and health professionals.